Driving forces of vancomycin-resistant E. faecium and E. faecalis blood-stream infections in children
نویسندگان
چکیده
منابع مشابه
Defining daptomycin resistance prevention exposures in vancomycin-resistant Enterococcus faecium and E. faecalis.
Daptomycin is used off-label for enterococcal infections; however, dosing targets for resistance prevention remain undefined. Doses of 4 to 6 mg/kg of body weight/day approved for staphylococci are likely inadequate against enterococci due to reduced susceptibility. We modeled daptomycin regimens in vitro to determine the minimum exposure to prevent daptomycin resistance (Dapr) in enterococci. ...
متن کاملprevalence of virulence factors and vancomycin-resistant genes among enterococcus faecalis and e. faecium isolated from clinical specimens
background: the aim of this study was to determine the occurrence of virulence determinants and vancomycin- resistant genes among enterococcus faecalis and e. faecium obtained from various clinical sources. methods: the study was performed on the 280 enterococcal isolated from clinical specimens in hamadan hospitals, western iran in 2012-14. antibiotic susceptibility testing was performed using...
متن کاملVanD-type vancomycin-resistant Enterococcus faecium and Enterococcus faecalis.
Enterococcus faecium clinical isolates A902 and BM4538, which were resistant to relatively high levels of vancomycin (128 and 64 microg/ml, respectively) and to low levels of teicoplanin (4 microg/ml), and Enterococcus faecalis clinical isolates BM4539 and BM4540, which were resistant to moderate levels of vancomycin (16 microg/ml) and susceptible to teicoplanin (0.25 microg/ml), were studied. ...
متن کاملVancomycin-resistant Enterococcus faecium colonization in children.
Nosocomial vancomycin-resistant Enterococcus (VRE) infections have been described in only small numbers of pediatric patients. In none of these studies were multivariate analyses performed to assess which factors were independent risk factors in these patients. In the present cohort study of patients admitted to our hematology/oncology unit, surveillance cultures revealed a colonization rate of...
متن کاملPrevalence of Virulence Factors and Vancomycin-resistant Genes among Enterococcus faecalis and E. faecium Isolated from Clinical Specimens
BACKGROUND The aim of this study was to determine the occurrence of virulence determinants and vancomycin-resistant genes among Enterococcus faecalis and E. faecium obtained from various clinical sources. METHODS The study was performed on the 280 enterococcal isolated from clinical specimens in Hamadan hospitals, western Iran in 2012-14. Antibiotic susceptibility testing was performed using ...
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ژورنال
عنوان ژورنال: Antimicrobial Resistance and Infection Control
سال: 2014
ISSN: 2047-2994
DOI: 10.1186/2047-2994-3-29